American Way: “Cultivating Second Chances”
By Charlotte Huff
 Derek Johnson didn't give much thought to the protective cartilage that cushioned his bones until a small area in his left knee wore down to the point that it was raw and painful. Following an evening on the basketball court, the 44-year-old woke up in the morning and knew he was in trouble: "I could barely walk," he says.
 
   After babying the joint and consulting with an orthopedic surgeon, Johnson dialed back his physical activity for several years - no competitive basketball and more "timid" tennis and football sessions, as he describes it. But the pain flared up again last summer. Johnson returned to his surgeon at New York City's Hospital for Special Surgery (HSS) and learned that his once tiny area of cartilage loss was expanding. Soon thereafter, the 49-year-old father of two opted to try an experimental procedure - one that would use his own harvested cartilage cells to grow a new protective layer of tissue.
 
   With limited cartilage-regeneration options available, Johnson believed this technique represented his best hope of one day resuming his sports passions. "I wasn't prepared - or willing - to become victim to a constrained way of life." he says.
 
   The procedure, in which harvested cells grow along a three-dimensional scaffold-like collagen device called a NeoCart, is one of several cartilage-regeneration approaches being explored by researchers in the United States and elsewhere who are striving to find a simple and cost-effective solution for a common problem: limited but painful cartilage loss in the knee. Contact for complete article.